Some
of my patients and family have asked me the effective way to reduce
cancer. As I searched extensive medical literature and the latest
research, I found two most effective ways that we could control: stop smoking
and achieves ideal body weight. In addition to heart disease, joints
problem, back pain, sleep apnea, diabetes, etc, obesity increases cancer risks
in
- Esophagus
- Pancreas
- Colon and rectum
- Breast (after menopause)
- Endometrium (lining of the uterus)
- Kidney
- Thyroid
- Gallbladder
The
mechanisms linking obesity and cancer are well described in the NCI websites:
- Fat tissue produces excess amounts of estrogen, high levels of which have been associated with the risk of breast, endometrial, and some other cancers.
- Obese people often have increased levels of insulin and insulin-like growth factor-1 (IGF-1) in their blood (a condition known as hyperinsulinemia or insulin resistance), which may promote the development of certain tumors.
- Fat cells produce hormones, called adipokines, that may stimulate or inhibit cell growth. For example, leptin, which is more abundant in obese people, seems to promote cell proliferation, whereas adiponectin, which is less abundant in obese people, may have antiproliferative effects.
- Fat cells may also have direct and indirect effects on other tumor growth regulators, including mammalian target of rapamycin (mTOR) and AMP-activated protein kinase.
- Obese people often have chronic low-level, or “subacute,” inflammation, which has been associated with increased cancer risk.
So,
how do I lose weight. Losing weight is hard but it is so worth it because
you are worth it. Please see my previous blog on weight loss.
Reference:
http://www.cancer.gov/cancertopics/factsheet/Risk/obesity
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