In some patients with ovarian cancer, unfortunately, the cancer spreads widely that surgery cannot remove most of the tumor. A randomized trial reported of using neoadjuvant chemo (chemo before surgery) first for 3 months to shrink tumor to smaller size, then surgery. In my experience, this approach works especially well on patients with a lots of tumor and ascites (fluid in abdomen) which put patient at high risk for surgical complications. Some patients, due to extensive tumor, may need longer than 3 months of neoadjuvant chemo. Although chemotherapy itself has its own side effects, some patients seem to better tolerate surgery after, rather than before chemo.
If you have widespread ovarian cancer with ascites, you may want to discuss this neoadjuvant chemotherapy approach with your doctor.
Reference:
Vergote I. et, al. New England Journal of Medicine. September 2010
If you have widespread ovarian cancer with ascites, you may want to discuss this neoadjuvant chemotherapy approach with your doctor.
Reference:
Vergote I. et, al. New England Journal of Medicine. September 2010
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